GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs2985684 | 1 | rs17121651 | chr14:50097172 | RPL36AL | chr14:50085407-50087349:- | 0.54 | 5.79 | 3.51E-7 | Carotid intima media thickness |
| UVM | cis | rs10242455 | 1 | rs17161692 | chr7:98953863 | PTCD1 | chr7:99016751-99063808:- | -0.7 | -4.7 | 1.8E-5 | Blood metabolite levels |
| UVM | cis | rs17433780 | 1 | rs17433780 | chr1:89474818 | GBP3 | chr1:89472367-89488549:- | 0.43 | 5.75 | 4.01E-7 | Carotid intima media thickness |
| UVM | cis | rs78153629 | 1 | rs17671194 | chr15:40667539 | C15orf23 | chr15:40674922-40686488:+ | 0.92 | 6.6 | 1.72E-8 | Heschl's gyrus morphology |
| UVM | cis | rs78153629 | 1 | rs17671250 | chr15:40673124 | C15orf23 | chr15:40674922-40686488:+ | -0.85 | -5.36 | 1.69E-6 | Heschl's gyrus morphology |
| UVM | cis | rs10935120 | 1 | rs17694011 | chr3:134213981 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |
| UVM | cis | rs11190604 | 1 | rs17746014 | chr10:102315354 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs1800662 | chr10:102289078 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs10935120 | 1 | rs1814336 | chr3:134200823 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.01 | 3.68E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs1814337 | chr3:134200682 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.01 | 3.68E-9 | Height |
| UVM | cis | rs10461617 | 1 | rs1833896 | chr5:56097669 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.34 | 4.59E-8 | Type 2 diabetes |
| UVM | cis | rs7973719 | 1 | rs1839622 | chr12:7334534 | PEX5 | chr12:7341759-7371167:+ | 0.74 | 10.3 | 1.94E-14 | IgG glycosylation |
| UVM | cis | rs10461617 | 1 | rs1862619 | chr5:56098256 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.34 | 4.59E-8 | Type 2 diabetes |
| UVM | cis | rs10935120 | 1 | rs1863913 | chr3:134200205 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.11 | 2.47E-9 | Height |
| UVM | cis | rs2564921 | 1 | rs1864367 | chr3:53111704 | RFT1 | chr3:53122503-53164470:- | -0.35 | -5.06 | 5.04E-6 | Height |